PT-141 is a synthetic peptide analogue of the naturally occurring $\alpha\text{-Melanocyte Stimulating Hormone}$ ($\alpha\text{-MSH}$). Unlike traditional treatments for sexual dysfunction that target the vascular system (blood flow), PT-141 is unique because it acts directly on the central nervous system. By binding to and activating melanocortin receptors in the brain—specifically the MC3R and MC4R subtypes—it triggers internal pathways associated with sexual motivation and desire.
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